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Prefusion structure of human cytomegalovirus glycoprotein B and structural basis for membrane fusion
Human cytomegalovirus (HCMV) causes congenital disease with long-term morbidity. HCMV glycoprotein B (gB) transitions irreversibly from a metastable prefusion to a stable postfusion conformation to fuse the viral envelope with a host cell membrane during entry. We stabilized prefusion gB on the viri...
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| Vydáno v: | Sci Adv |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Association for the Advancement of Science
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7935361/ https://ncbi.nlm.nih.gov/pubmed/33674318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abf3178 |
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