The prefusion structure of herpes simplex virus glycoprotein B

Cell entry of enveloped viruses requires specialized viral proteins that mediate fusion with the host membrane by substantial structural rearrangements from a metastable pre- to a stable postfusion conformation. This metastability renders the herpes simplex virus 1 (HSV-1) fusion glycoprotein B (gB)...

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Udgivet i:Sci Adv
Main Authors: Vollmer, B., Pražák, V., Vasishtan, D., Jefferys, E. E., Hernandez-Duran, A., Vallbracht, M., Klupp, B. G., Mettenleiter, T. C., Backovic, M., Rey, F. A., Topf, M., Grünewald, K.
Format: Artigo
Sprog:Inglês
Udgivet: American Association for the Advancement of Science 2020
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7518877/
https://ncbi.nlm.nih.gov/pubmed/32978151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abc1726
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