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Functional Characterization of Glycoprotein H Chimeras Composed of Conserved Domains of the Pseudorabies Virus and Herpes Simplex Virus 1 Homologs

Membrane fusion is indispensable for entry of enveloped viruses into host cells. The conserved core fusion machinery of the Herpesviridae consists of glycoprotein B (gB) and the gH/gL complex. Recently, crystal structures of gH/gL of herpes simplex virus 2 (HSV-2) and Epstein-Barr virus and of a cor...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Böhm, Sebastian W., Backovic, Marija, Klupp, Barbara G., Rey, Felix A., Mettenleiter, Thomas C., Fuchs, Walter
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702552/
https://ncbi.nlm.nih.gov/pubmed/26491153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01985-15
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