Single-cell analyses identify circulating anti-tumor CD8 T cells and markers for their enrichment

The ability to monitor anti-tumor CD8(+) T cell responses in the blood has tremendous therapeutic potential. Here, we used paired single-cell RNA and TCR sequencing to detect and characterize “tumor-matching” (TM) CD8(+) T cells in the blood of mice with MC38 tumors or melanoma patients using the TC...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:J Exp Med
Asıl Yazarlar: Pauken, Kristen E., Shahid, Osmaan, Lagattuta, Kaitlyn A., Mahuron, Kelly M., Luber, Jacob M., Lowe, Margaret M., Huang, Linglin, Delaney, Conor, Long, Jaclyn M., Fung, Megan E., Newcomer, Kathleen, Tsai, Katy K., Chow, Melissa, Guinn, Samantha, Kuchroo, Juhi R., Burke, Kelly P., Schenkel, Jason M., Rosenblum, Michael D., Daud, Adil I., Sharpe, Arlene H., Singer, Meromit
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Rockefeller University Press 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7933992/
https://ncbi.nlm.nih.gov/pubmed/33651880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20200920
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller