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Single-cell analyses identify circulating anti-tumor CD8 T cells and markers for their enrichment
The ability to monitor anti-tumor CD8(+) T cell responses in the blood has tremendous therapeutic potential. Here, we used paired single-cell RNA and TCR sequencing to detect and characterize “tumor-matching” (TM) CD8(+) T cells in the blood of mice with MC38 tumors or melanoma patients using the TC...
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| Publicado no: | J Exp Med |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7933992/ https://ncbi.nlm.nih.gov/pubmed/33651880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20200920 |
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