A bilateral tumor model identifies transcriptional programs associated with patient response to immune checkpoint blockade

Immune checkpoint blockade (ICB) is efficacious in many diverse cancer types, but not all patients respond. It is important to understand the mechanisms driving resistance to these treatments and to identify predictive biomarkers of response to provide best treatment options for all patients. Here w...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Chen, Ivy X., Newcomer, Kathleen, Pauken, Kristen E., Juneja, Vikram R., Naxerova, Kamila, Wu, Michelle W., Pinter, Matthias, Sen, Debattama R., Singer, Meromit, Sharpe, Arlene H., Jain, Rakesh K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7519254/
https://ncbi.nlm.nih.gov/pubmed/32907939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2002806117
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