Single-cell analyses identify circulating anti-tumor CD8 T cells and markers for their enrichment

The ability to monitor anti-tumor CD8(+) T cell responses in the blood has tremendous therapeutic potential. Here, we used paired single-cell RNA and TCR sequencing to detect and characterize “tumor-matching” (TM) CD8(+) T cells in the blood of mice with MC38 tumors or melanoma patients using the TC...

詳細記述

保存先:
書誌詳細
出版年:J Exp Med
主要な著者: Pauken, Kristen E., Shahid, Osmaan, Lagattuta, Kaitlyn A., Mahuron, Kelly M., Luber, Jacob M., Lowe, Margaret M., Huang, Linglin, Delaney, Conor, Long, Jaclyn M., Fung, Megan E., Newcomer, Kathleen, Tsai, Katy K., Chow, Melissa, Guinn, Samantha, Kuchroo, Juhi R., Burke, Kelly P., Schenkel, Jason M., Rosenblum, Michael D., Daud, Adil I., Sharpe, Arlene H., Singer, Meromit
フォーマット: Artigo
言語:Inglês
出版事項: Rockefeller University Press 2021
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7933992/
https://ncbi.nlm.nih.gov/pubmed/33651880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20200920
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