Multiple Myeloma Cells Alter Adipogenesis, Increase Senescence-Related and Inflammatory Gene Transcript Expression, and Alter Metabolism in Preadipocytes

Within the bone marrow microenvironment, mesenchymal stromal cells (MSCs) are an essential precursor to bone marrow adipocytes and osteoblasts. The balance between this progenitor pool and mature cells (adipocytes and osteoblasts) is often skewed by disease and aging. In multiple myeloma (MM), a can...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Oncol
Egile Nagusiak: Fairfield, Heather, Costa, Samantha, Falank, Carolyne, Farrell, Mariah, Murphy, Connor S., D’Amico, Anastasia, Driscoll, Heather, Reagan, Michaela R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2021
Gaiak:
Oncology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7930573/
https://ncbi.nlm.nih.gov/pubmed/33680918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.584683
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