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Sclerostin-Neutralizing Antibody Treatment Rescues Negative Effects of Rosiglitazone on Mouse Bone Parameters

Obesity, a growing pandemic, is a risk factor for many cancers and causes increased bone marrow adipose tissue (BMAT). In vitro studies and obese animal models suggest that BMAT contributes to cancer progression, but there is a lack of preclinical models to directly test BMAT’s role in cancer. Over...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Farrell, Mariah, Fairfield, Heather, Costa, Samantha, D’Amico, Anastasia, Falank, Carolyne, Brooks, Daniel J., Reagan, Michaela R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8080259/
https://ncbi.nlm.nih.gov/pubmed/32845528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.4170
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