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Multiple myeloma in the marrow: pathogenesis and treatments

Multiple myeloma (MM) is a B-cell malignancy resulting in osteolytic lesions and fractures. In the disease state, bone healing is limited due to increased osteoclastic and decreased osteoblastic activity, as well as an MM-induced forward-feedback cycle where bone-embedded growth factors further enha...

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Detalhes bibliográficos
Publicado no:Ann N Y Acad Sci
Main Authors: Fairfield, Heather, Falank, Carolyne, Avery, Lindsey, Reagan, Michaela R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4806534/
https://ncbi.nlm.nih.gov/pubmed/27002787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.13038
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