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Multiple myeloma in the marrow: pathogenesis and treatments
Multiple myeloma (MM) is a B-cell malignancy resulting in osteolytic lesions and fractures. In the disease state, bone healing is limited due to increased osteoclastic and decreased osteoblastic activity, as well as an MM-induced forward-feedback cycle where bone-embedded growth factors further enha...
Shranjeno v:
izdano v: | Ann N Y Acad Sci |
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Main Authors: | , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
2016
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4806534/ https://ncbi.nlm.nih.gov/pubmed/27002787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.13038 |
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