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Standardization of the liquid biopsy for pediatric diffuse midline glioma using ddPCR
Diffuse midline glioma (DMG) is a highly morbid pediatric brain tumor. Up to 80% of DMGs harbor mutations in histone H3-encoding genes, associated with poor prognosis. We previously showed the feasibility of detecting H3 mutations in circulating tumor DNA (ctDNA) in the liquid biome of children diag...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7930089/ https://ncbi.nlm.nih.gov/pubmed/33658570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-84513-1 |
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