PDTM-42. CROSS-PLATFORM PROFILING OF ctDNA USING ddPCR: STANDARDIZATION OF THE LIQUID BIOPSY FOR PEDIATRIC DIFFUSE MIDLINE GLIOMA

INTRODUCTION: Pediatric diffuse midline glioma (DMG) with histone H3 mutations (80%), are highly morbid tumors with poor response to therapy. We previously detected H3 mutations in circulating tumor DNA (ctDNA) from CSF derived from children with DMG and high grade glioma. Here, we describe a high-t...

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Bibliographic Details
Published in:Neuro Oncol
Main Authors: Li, Daphne, Bonner, Erin, Stallard, Stefanie, Panditharatna, Eshini, Huang, Tina, Lulla, Rishi, Koschmann, Carl, Nazarian, Javad, Saratsis, Amanda
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
Pediatric Tumors
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847192/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.817
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