PDTM-42. CROSS-PLATFORM PROFILING OF ctDNA USING ddPCR: STANDARDIZATION OF THE LIQUID BIOPSY FOR PEDIATRIC DIFFUSE MIDLINE GLIOMA

INTRODUCTION: Pediatric diffuse midline glioma (DMG) with histone H3 mutations (80%), are highly morbid tumors with poor response to therapy. We previously detected H3 mutations in circulating tumor DNA (ctDNA) from CSF derived from children with DMG and high grade glioma. Here, we describe a high-t...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Li, Daphne, Bonner, Erin, Stallard, Stefanie, Panditharatna, Eshini, Huang, Tina, Lulla, Rishi, Koschmann, Carl, Nazarian, Javad, Saratsis, Amanda
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2019
Teme:
Pediatric Tumors
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847192/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.817
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