PDTM-42. CROSS-PLATFORM PROFILING OF ctDNA USING ddPCR: STANDARDIZATION OF THE LIQUID BIOPSY FOR PEDIATRIC DIFFUSE MIDLINE GLIOMA

INTRODUCTION: Pediatric diffuse midline glioma (DMG) with histone H3 mutations (80%), are highly morbid tumors with poor response to therapy. We previously detected H3 mutations in circulating tumor DNA (ctDNA) from CSF derived from children with DMG and high grade glioma. Here, we describe a high-t...

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Detaylı Bibliyografya
Yayımlandı:Neuro Oncol
Asıl Yazarlar: Li, Daphne, Bonner, Erin, Stallard, Stefanie, Panditharatna, Eshini, Huang, Tina, Lulla, Rishi, Koschmann, Carl, Nazarian, Javad, Saratsis, Amanda
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2019
Konular:
Pediatric Tumors
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847192/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.817
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