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Standardization of the liquid biopsy for pediatric diffuse midline glioma using ddPCR
Diffuse midline glioma (DMG) is a highly morbid pediatric brain tumor. Up to 80% of DMGs harbor mutations in histone H3-encoding genes, associated with poor prognosis. We previously showed the feasibility of detecting H3 mutations in circulating tumor DNA (ctDNA) in the liquid biome of children diag...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group UK
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7930089/ https://ncbi.nlm.nih.gov/pubmed/33658570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-84513-1 |
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