Standardization of the liquid biopsy for pediatric diffuse midline glioma using ddPCR

Diffuse midline glioma (DMG) is a highly morbid pediatric brain tumor. Up to 80% of DMGs harbor mutations in histone H3-encoding genes, associated with poor prognosis. We previously showed the feasibility of detecting H3 mutations in circulating tumor DNA (ctDNA) in the liquid biome of children diag...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Li, Daphne, Bonner, Erin R., Wierzbicki, Kyle, Panditharatna, Eshini, Huang, Tina, Lulla, Rishi, Mueller, Sabine, Koschmann, Carl, Nazarian, Javad, Saratsis, Amanda M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7930089/
https://ncbi.nlm.nih.gov/pubmed/33658570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-84513-1
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