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Tumor-derived ILT4 induces T cell senescence and suppresses tumor immunity

BACKGROUND: Current immunotherapies including checkpoint blockade therapy have limited success rates in certain types of cancers. Identification of alternative checkpoint molecules for the development of effective strategies for tumor immunotherapy is urgently needed. Immunoglobulin-like transcript...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Gao, Aiqin, Liu, Xia, Lin, Wenli, Wang, Jingnan, Wang, Shuyun, Si, Fusheng, Huang, Lan, Zhao, Yangjing, Sun, Yuping, Peng, Guangyong
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7929805/
https://ncbi.nlm.nih.gov/pubmed/33653799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001536
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