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Exhaustion and senescence: two crucial dysfunctional states of T cells in the tumor microenvironment
The failure of a massive influx of tumor-infiltrating T lymphocytes to eradicate tumor cells in the tumor microenvironment is mainly due to the dysfunction of T cells hyporesponsive to tumors. T-cell exhaustion and senescence induced by malignant tumors are two important dysfunctional states that co...
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| 出版年: | Cell Mol Immunol |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6952436/ https://ncbi.nlm.nih.gov/pubmed/31853000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-019-0344-8 |
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