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Tumor-derived ILT4 induces T cell senescence and suppresses tumor immunity

BACKGROUND: Current immunotherapies including checkpoint blockade therapy have limited success rates in certain types of cancers. Identification of alternative checkpoint molecules for the development of effective strategies for tumor immunotherapy is urgently needed. Immunoglobulin-like transcript...

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Bibliografiske detaljer
Udgivet i:J Immunother Cancer
Main Authors: Gao, Aiqin, Liu, Xia, Lin, Wenli, Wang, Jingnan, Wang, Shuyun, Si, Fusheng, Huang, Lan, Zhao, Yangjing, Sun, Yuping, Peng, Guangyong
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Publishing Group 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7929805/
https://ncbi.nlm.nih.gov/pubmed/33653799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001536
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