Tumor-derived ILT4 induces T cell senescence and suppresses tumor immunity

BACKGROUND: Current immunotherapies including checkpoint blockade therapy have limited success rates in certain types of cancers. Identification of alternative checkpoint molecules for the development of effective strategies for tumor immunotherapy is urgently needed. Immunoglobulin-like transcript...

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Veröffentlicht in:J Immunother Cancer
Hauptverfasser: Gao, Aiqin, Liu, Xia, Lin, Wenli, Wang, Jingnan, Wang, Shuyun, Si, Fusheng, Huang, Lan, Zhao, Yangjing, Sun, Yuping, Peng, Guangyong
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2021
Schlagworte:
Basic Tumor Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7929805/
https://ncbi.nlm.nih.gov/pubmed/33653799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001536
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