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Exonuclease VII repairs quinolone-induced damage by resolving DNA gyrase cleavage complexes
The widely used quinolone antibiotics act by trapping prokaryotic type IIA topoisomerases, resulting in irreversible topoisomerase cleavage complexes (TOPcc). Whereas the excision repair pathways of TOPcc in eukaryotes have been extensively studied, it is not known whether equivalent repair pathways...
Zapisane w:
| Wydane w: | Sci Adv |
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| Główni autorzy: | , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Association for the Advancement of Science
2021
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7929499/ https://ncbi.nlm.nih.gov/pubmed/33658195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abe0384 |
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