Exonuclease VII repairs quinolone-induced damage by resolving DNA gyrase cleavage complexes

The widely used quinolone antibiotics act by trapping prokaryotic type IIA topoisomerases, resulting in irreversible topoisomerase cleavage complexes (TOPcc). Whereas the excision repair pathways of TOPcc in eukaryotes have been extensively studied, it is not known whether equivalent repair pathways...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Adv
Päätekijät: Huang, Shar-yin N., Michaels, Stephanie A., Mitchell, Brianna B., Majdalani, Nadim, Vanden Broeck, Arnaud, Canela, Andres, Tse-Dinh, Yuk-Ching, Lamour, Valerie, Pommier, Yves
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Association for the Advancement of Science 2021
Aiheet:
Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7929499/
https://ncbi.nlm.nih.gov/pubmed/33658195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abe0384
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