Mrc1-Dependent Chromatin Compaction Represses DNA Double-Stranded Break Repair by Homologous Recombination Upon Replication Stress

The coordination of DNA replication and repair is critical for the maintenance of genome stability. It has been shown that the Mrc1-mediated S phase checkpoint inhibits DNA double-stranded break (DSB) repair through homologous recombination (HR). How the replication checkpoint inhibits HR remains on...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Front Cell Dev Biol
Hlavní autoři: Xing, Poyuan, Dong, Yang, Zhao, Jingyu, Zhou, Zhou, Li, Zhao, Wang, Yu, Li, Mengfei, Zhang, Xinghua, Chen, Xuefeng
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Cell and Developmental Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7928320/
https://ncbi.nlm.nih.gov/pubmed/33681209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.630777
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky