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Processing of DNA double strand breaks by alternative non-homologous end-joining in hyperacetylated chromatin

BACKGROUND: Mammalian cells employ at least two subpathways of non-homologous end-joining for the repair of ionizing radiation induced DNA double strand breaks: The canonical DNA-PK-dependent form of non-homologous end-joining (D-NHEJ) and an alternative, slowly operating, error-prone backup pathway...

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Bibliografiska uppgifter
Huvudupphovsmän: Manova, Vasilissa, Singh, Satyendra K, Iliakis, George
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471266/
https://ncbi.nlm.nih.gov/pubmed/22908892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2041-9414-3-4
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