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Microglial activation induced by the alarmin S100B is regulated by poly(ADP-ribose) polymerase-1

Brain injury resulting from stroke or trauma can be exacerbated by the release of pro-inflammatory cytokines, proteases, and reactive oxygen species by activated microglia. The microglial activation resulting from brain injury is mediated in part by alarmins, which are signaling molecules released f...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Glia
Hauptverfasser: Xu, Jianguo, Wang, Handong, Won, Seok Joon, Basu, Jayinee, Kapfhamer, David, Swanson, Raymond A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7927976/
https://ncbi.nlm.nih.gov/pubmed/27444121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.23026
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