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Ischemic Preconditioning by Caspase Cleavage of Poly(ADP-Ribose) Polymerase-1
A transient, sublethal ischemic interval confers resistance to a subsequent, otherwise lethal ischemic insult, in a process termed ischemic preconditioning. Poly(ADP-ribose) polymerase-1 (PARP-1) normally functions in DNA repair, but extensive PARP-1 activation is a major cause of ischemic cell deat...
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| Publicat a: | J Neurosci |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Society for Neuroscience
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6740500/ https://ncbi.nlm.nih.gov/pubmed/12954857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-22-07967.2003 |
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