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Functionalization of the BCL6 BTB domain into a noncovalent crystallization chaperone

The production of diffraction-quality protein crystals is challenging and often requires bespoke, time-consuming and expensive strategies. A system has been developed in which the BCL6 BTB domain acts as a crystallization chaperone and promiscuous assembly block that may form the basis for affinity-...

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Detalles Bibliográficos
Publicado en:IUCrJ
Main Authors: Zacharchenko, Thomas, Wright, Stephanie
Formato: Artigo
Idioma:Inglês
Publicado: International Union of Crystallography 2021
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7924223/
https://ncbi.nlm.nih.gov/pubmed/33708392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2052252520015754
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