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Cutting Edge: T Follicular Helper Cell Differentiation Is Defective in the Absence of Bcl6 BTB Repressor Domain Function

T follicular helper (Tfh) cells are essential for germinal centers (GCs) and most long-term humoral immunity. Differentiation of Tfh cells depends on the transcriptional repressor B cell CLL/lymphoma 6 (Bcl6). Bcl6 mediates gene repression via the recruitment of corepressors. Currently, it is unknow...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Nance, J. Philip, Bélanger, Simon, Johnston, Robert J., Takemori, Toshitada, Crotty, Shane
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456636/
https://ncbi.nlm.nih.gov/pubmed/25957170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500200
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