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Cutting Edge: Circulating Plasmablasts Induce the Differentiation of Human T Follicular Helper Cells via IL-6 Production

B cells require CD4(+) T follicular helper (Tfh) cells to progress through the germinal center and provide protective Ab responses. In this article, we reveal a reciprocal interaction whereby circulating human plasmablasts are potent inducers of the Tfh cell–differentiation program, including the ex...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Chavele, Konstantia-Maria, Merry, Eve, Ehrenstein, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356730/
https://ncbi.nlm.nih.gov/pubmed/25681343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401190
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