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Cutting Edge: The NLRP3 Inflammasome Links Complement-Mediated Inflammation and IL-1β Release

The complement system is a potent component of the innate immune response, promoting inflammation and orchestrating defense against pathogens. However, dysregulation of complement is critical to several autoimmune and inflammatory syndromes. Elevated expression of the proinflammatory cytokine IL-1β...

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Библиографические подробности
Главные авторы: Laudisi, Federica, Spreafico, Roberto, Evrard, Maximilien, Hughes, Timothy R., Mandriani, Barbara, Kandasamy, Matheswaran, Morgan, B. Paul, Sivasankar, Baalasubramanian, Mortellaro, Alessandra
Формат: Artigo
Язык:Inglês
Опубликовано: AAI 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718202/
https://ncbi.nlm.nih.gov/pubmed/23817414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300489
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