Cutting Edge: The NLRP3 Inflammasome Links Complement-Mediated Inflammation and IL-1β Release

The complement system is a potent component of the innate immune response, promoting inflammation and orchestrating defense against pathogens. However, dysregulation of complement is critical to several autoimmune and inflammatory syndromes. Elevated expression of the proinflammatory cytokine IL-1β...

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Detalhes bibliográficos
Main Authors: Laudisi, Federica, Spreafico, Roberto, Evrard, Maximilien, Hughes, Timothy R., Mandriani, Barbara, Kandasamy, Matheswaran, Morgan, B. Paul, Sivasankar, Baalasubramanian, Mortellaro, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2013
Assuntos:
Cutting Edge
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718202/
https://ncbi.nlm.nih.gov/pubmed/23817414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300489
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