Cutting Edge: The NLRP3 Inflammasome Links Complement-Mediated Inflammation and IL-1β Release

The complement system is a potent component of the innate immune response, promoting inflammation and orchestrating defense against pathogens. However, dysregulation of complement is critical to several autoimmune and inflammatory syndromes. Elevated expression of the proinflammatory cytokine IL-1β...

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Main Authors: Laudisi, Federica, Spreafico, Roberto, Evrard, Maximilien, Hughes, Timothy R., Mandriani, Barbara, Kandasamy, Matheswaran, Morgan, B. Paul, Sivasankar, Baalasubramanian, Mortellaro, Alessandra
Format: Artigo
Sprog:Inglês
Udgivet: AAI 2013
Fag:
Cutting Edge
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718202/
https://ncbi.nlm.nih.gov/pubmed/23817414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300489
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