Cutting Edge: The NLRP3 Inflammasome Links Complement-Mediated Inflammation and IL-1β Release

The complement system is a potent component of the innate immune response, promoting inflammation and orchestrating defense against pathogens. However, dysregulation of complement is critical to several autoimmune and inflammatory syndromes. Elevated expression of the proinflammatory cytokine IL-1β...

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Autori principali: Laudisi, Federica, Spreafico, Roberto, Evrard, Maximilien, Hughes, Timothy R., Mandriani, Barbara, Kandasamy, Matheswaran, Morgan, B. Paul, Sivasankar, Baalasubramanian, Mortellaro, Alessandra
Natura: Artigo
Lingua:Inglês
Pubblicazione: AAI 2013
Soggetti:
Cutting Edge
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718202/
https://ncbi.nlm.nih.gov/pubmed/23817414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300489
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