C5a Regulates IL-1β Production and Leukocyte Recruitment in a Murine Model of Monosodium Urate Crystal-Induced Peritonitis

Gouty arthritis results from the generation of monosodium urate (MSU) crystals within joints. These MSU crystals elicit acute inflammation characterized by massive infiltration of neutrophils and monocytes that are mobilized by the pro-inflammatory cytokine IL-1β. MSU crystals also activate the comp...

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Bibliografische gegevens
Gepubliceerd in:Front Pharmacol
Hoofdauteurs: Khameneh, Hanif J., Ho, Adrian W. S., Laudisi, Federica, Derks, Heidi, Kandasamy, Matheswaran, Sivasankar, Baalasubramanian, Teng, Gim Gee, Mortellaro, Alessandra
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2017
Onderwerpen:
Pharmacology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5253373/
https://ncbi.nlm.nih.gov/pubmed/28167912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00010
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