C5a Regulates IL-1β Production and Leukocyte Recruitment in a Murine Model of Monosodium Urate Crystal-Induced Peritonitis

Gouty arthritis results from the generation of monosodium urate (MSU) crystals within joints. These MSU crystals elicit acute inflammation characterized by massive infiltration of neutrophils and monocytes that are mobilized by the pro-inflammatory cytokine IL-1β. MSU crystals also activate the comp...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Pharmacol
Auteurs principaux: Khameneh, Hanif J., Ho, Adrian W. S., Laudisi, Federica, Derks, Heidi, Kandasamy, Matheswaran, Sivasankar, Baalasubramanian, Teng, Gim Gee, Mortellaro, Alessandra
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2017
Sujets:
Pharmacology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5253373/
https://ncbi.nlm.nih.gov/pubmed/28167912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00010
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