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Cutting Edge: Inflammasome Activation in Primary Human Macrophages Is Dependent on Flagellin

Murine NLR family, apoptosis inhibitory protein (Naip)1, Naip2, and Naip5/6 are host sensors that detect the cytosolic presence of needle and rod proteins from bacterial type III secretion systems and flagellin, respectively. Previous studies using human-derived macrophage-like cell lines indicate t...

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Détails bibliographiques
Publié dans:J Immunol
Auteurs principaux: Kortmann, Jens, Brubaker, Sky W., Monack, Denise M.
Format: Artigo
Langue:Inglês
Publié: AAI 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505955/
https://ncbi.nlm.nih.gov/pubmed/26109648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1403100
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