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Cutting Edge: The Heat Shock Protein gp96 Activates Inflammasome-Signaling Platforms in APCs
Several heat shock proteins (HSPs) prime immune responses, which are, in part, a result of activation of APCs. APCs respond to these immunogenic HSPs by upregulating costimulatory molecules and secreting cytokines, including IL-1β. These HSP-mediated responses are central mediators in pathological c...
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| Pubblicato in: | J Immunol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
AAI
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6176107/ https://ncbi.nlm.nih.gov/pubmed/30209191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800505 |
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