Cutting Edge: The NLRP3 Inflammasome Links Complement-Mediated Inflammation and IL-1β Release

The complement system is a potent component of the innate immune response, promoting inflammation and orchestrating defense against pathogens. However, dysregulation of complement is critical to several autoimmune and inflammatory syndromes. Elevated expression of the proinflammatory cytokine IL-1β...

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Bibliografski detalji
Glavni autori: Laudisi, Federica, Spreafico, Roberto, Evrard, Maximilien, Hughes, Timothy R., Mandriani, Barbara, Kandasamy, Matheswaran, Morgan, B. Paul, Sivasankar, Baalasubramanian, Mortellaro, Alessandra
Format: Artigo
Jezik:Inglês
Izdano: AAI 2013
Teme:
Cutting Edge
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718202/
https://ncbi.nlm.nih.gov/pubmed/23817414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300489
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