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Bcl6 middle domain repressor function is required for T follicular helper cell differentiation and utilizes the corepressor MTA3

T follicular helper (Tfh) cells are essential providers of help to B cells. The transcription factor B-cell CLL/lymphoma 6 (Bcl6) is a lineage-defining regulator of Tfh cells and germinal center B cells. In B cells, Bcl6 has the potential to recruit distinct transcriptional corepressors through its...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Nance, J. Philip, Bélanger, Simon, Johnston, Robert J., Hu, Joyce K., Takemori, Toshitada, Crotty, Shane
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4629362/
https://ncbi.nlm.nih.gov/pubmed/26460037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1507312112
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