Bcl-6 is the nexus transcription factor of T follicular helper cells (T(FH)) via repressor-of-repressor circuits

T follicular helper (T(FH)) cells are a distinct type of CD4(+) T cells that are essential for most antibody and B lymphocyte responses. T(FH) cell regulation and dysregulation is involved in a range of diseases. Bcl-6 is the lineage defining transcription factor of T(FH) cells and its activity is e...

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Publicado no:Nat Immunol
Main Authors: Choi, Jinyong, Diao, Huitian, Faliti, Caterina E., Truong, Jacquelyn, Rossi, Meghan, Bélanger, Simon, Yu, Bingfei, Goldrath, Ananda W., Pipkin, Matthew E., Crotty, Shane
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7449381/
https://ncbi.nlm.nih.gov/pubmed/32572238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-020-0706-5
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