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Bcl-6 is the nexus transcription factor of T follicular helper cells (T(FH)) via repressor-of-repressor circuits
T follicular helper (T(FH)) cells are a distinct type of CD4(+) T cells that are essential for most antibody and B lymphocyte responses. T(FH) cell regulation and dysregulation is involved in a range of diseases. Bcl-6 is the lineage defining transcription factor of T(FH) cells and its activity is e...
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| 出版年: | Nat Immunol |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7449381/ https://ncbi.nlm.nih.gov/pubmed/32572238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-020-0706-5 |
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