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Structure of a BCOR corepressor peptide in complex with the BCL6 BTB domain dimer

The transcriptional corepressors BCOR, SMRT and NCoR are known to bind competitively to the BCL6 BTB domain despite the fact that BCOR has no detectible sequence similarity to the other two corepressors. We have identified a previously uncharacterized 17 residue motif from BCOR that binds directly t...

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Bibliographic Details
Main Authors: Ghetu, Alexandru F., Corcoran, Connie M., Cerchietti, Leandro, Bardwell, Vivian J., Melnick, Ari, Privé, Gilbert G.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665293/
https://ncbi.nlm.nih.gov/pubmed/18280243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.12.026
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