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Identification of a potent antagonist of smoothened in hedgehog signaling
BACKGROUND: Hedgehog signaling is essential to the regulation of embryonic development, tissue homeostasis, and stem cell self-renewal, making it a prime target for developing cancer therapeutics. Given the close link between aberrant Hedgehog signaling and cancers, many small molecular compounds ha...
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| Publicado no: | Cell Biosci |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7923671/ https://ncbi.nlm.nih.gov/pubmed/33653381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13578-021-00558-9 |
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