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Transient primary cilia mediate robust Hedgehog pathway-dependent cell cycle control

The regulation of proliferation is a primary function of Hedgehog (Hh) signaling in development. Hh signal transduction requires the primary cilium for several steps in the pathway [1–5]. Many cells only build a primary cilium upon cell cycle exit, in G0. In those proliferating cells that do make a...

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Bibliographic Details
Published in:Curr Biol
Main Authors: Ho, Emily K., Tsai, Anaïs E., Stearns, Tim
Format: Artigo
Language:Inglês
Published: 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7923399/
https://ncbi.nlm.nih.gov/pubmed/32531277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2020.05.004
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