Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling

Primary cilia are present on mammalian neurons and glia, but their function is largely unknown. We generated conditional homozygous mutant mice for a gene we termed Stumpy. Mutants lack cilia and have conspicuous abnormalities in postnatally developing brain regions, including a hypoplasic hippocamp...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Breunig, Joshua J., Sarkisian, Matthew R., Arellano, Jon I., Morozov, Yury M., Ayoub, Albert E., Sojitra, Sonal, Wang, Baolin, Flavell, Richard A., Rakic, Pasko, Town, Terrence
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2008
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2529104/
https://ncbi.nlm.nih.gov/pubmed/18728187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804558105
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares