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Primary cilia regulate hippocampal neurogenesis by mediating sonic hedgehog signaling
Primary cilia are present on mammalian neurons and glia, but their function is largely unknown. We generated conditional homozygous mutant mice for a gene we termed Stumpy. Mutants lack cilia and have conspicuous abnormalities in postnatally developing brain regions, including a hypoplasic hippocamp...
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| Hlavní autoři: | , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2529104/ https://ncbi.nlm.nih.gov/pubmed/18728187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804558105 |
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