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Sonic hedgehog promotes autophagy in hippocampal neurons

The Sonic hedgehog (Shh) signaling pathway is well known in patterning of the neural tube during embryonic development, but its emerging role in differentiated neurons is less understood. Here we report that Shh enhances autophagy in cultured hippocampal neurons. Microarray analysis reveals the upre...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Petralia, Ronald S., Schwartz, Catherine M., Wang, Ya-Xian, Kawamoto, Elisa M., Mattson, Mark P., Yao, Pamela J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654269/
https://ncbi.nlm.nih.gov/pubmed/23789099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20134275
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