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Sonic hedgehog promotes autophagy in hippocampal neurons

The Sonic hedgehog (Shh) signaling pathway is well known in patterning of the neural tube during embryonic development, but its emerging role in differentiated neurons is less understood. Here we report that Shh enhances autophagy in cultured hippocampal neurons. Microarray analysis reveals the upre...

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Detalhes bibliográficos
Main Authors: Petralia, Ronald S., Schwartz, Catherine M., Wang, Ya-Xian, Kawamoto, Elisa M., Mattson, Mark P., Yao, Pamela J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654269/
https://ncbi.nlm.nih.gov/pubmed/23789099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20134275
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