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Hedgehog signaling and the primary cilium: implications for spatial and temporal constraints on signaling

The mechanisms of vertebrate Hedgehog signaling are linked to the biology of the primary cilium, an antenna-like organelle that projects from the surface of most vertebrate cell types. Although the advantages of restricting signal transduction to cilia are often noted, the constraints imposed are le...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Development
Hauptverfasser: Ho, Emily K., Stearns, Tim
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8126410/
https://ncbi.nlm.nih.gov/pubmed/33914866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.195552
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