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The Primary Cilium as a Hedgehog Signal Transduction Machine
The Hedgehog (Hh) signal transduction pathway is essential for the development and patterning of numerous organ systems, and has important roles in a variety of human cancers. Genetic screens for mouse embryonic patterning mutants first showed a connection between mammalian Hh signaling and intrafla...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867239/ https://ncbi.nlm.nih.gov/pubmed/20362092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0091-679X(08)94010-3 |
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