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Primary Cilia Are Not Required for Normal Canonical Wnt Signaling in the Mouse Embryo

BACKGROUND: Sonic hedgehog (Shh) signaling in the mouse requires the microtubule-based organelle, the primary cilium. The primary cilium is assembled and maintained through the process of intraflagellar transport (IFT) and the response to Shh is blocked in mouse mutants that lack proteins required f...

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Autori principali: Ocbina, Polloneal Jymmiel R., Tuson, Miquel, Anderson, Kathryn V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729396/
https://ncbi.nlm.nih.gov/pubmed/19718259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006839
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