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Primary Cilia Are Not Required for Normal Canonical Wnt Signaling in the Mouse Embryo

BACKGROUND: Sonic hedgehog (Shh) signaling in the mouse requires the microtubule-based organelle, the primary cilium. The primary cilium is assembled and maintained through the process of intraflagellar transport (IFT) and the response to Shh is blocked in mouse mutants that lack proteins required f...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ocbina, Polloneal Jymmiel R., Tuson, Miquel, Anderson, Kathryn V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729396/
https://ncbi.nlm.nih.gov/pubmed/19718259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006839
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