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Signalling in the primary cilium through the lens of the Hedgehog pathway

Cilia are microtubule-based, cell-surface projections whose machinery is evolutionarily conserved. In vertebrates, cilia are observed on almost every cell type and are either motile or immotile. Immotile sensory, or primary cilia, are responsive to extracellular ligands and signals. Cilia can be tho...

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Detalles Bibliográficos
Publicado en:Wiley Interdiscip Rev Dev Biol
Main Authors: Gigante, Eduardo D., Caspary, Tamara
Formato: Artigo
Idioma:Inglês
Publicado: 2020
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7444278/
https://ncbi.nlm.nih.gov/pubmed/32084300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wdev.377
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