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Primary cilia can both mediate and suppress Hedgehog pathway–dependent tumorigenesis
Primary cilia are present on most mammalian cells and are implicated in transducing Hedgehog (Hh) signals during development; however, the prevalence of cilia on human tumors remains unclear, and the role of cilia in cancer has not been examined. Here we show that human basal cell carcinomas (BCCs)...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2895420/ https://ncbi.nlm.nih.gov/pubmed/19701205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2011 |
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