Caricamento...

Primary cilia can both mediate and suppress Hedgehog pathway–dependent tumorigenesis

Primary cilia are present on most mammalian cells and are implicated in transducing Hedgehog (Hh) signals during development; however, the prevalence of cilia on human tumors remains unclear, and the role of cilia in cancer has not been examined. Here we show that human basal cell carcinomas (BCCs)...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Wong, Sunny Y, Seol, Allen D, So, Po-Lin, Ermilov, Alexandre N, Bichakjian, Christopher K, Epstein, Ervin H, Dlugosz, Andrzej A, Reiter, Jeremy F
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895420/
https://ncbi.nlm.nih.gov/pubmed/19701205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2011
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !