Endothelial-Derived miR-17∼92 Promotes Angiogenesis to Protect against Renal Ischemia-Reperfusion Injury

BACKGROUND: Damage to the renal microvasculature is a hallmark of renal ischemia-reperfusion injury (IRI)–mediated AKI. The miR-17∼92 miRNA cluster (encoding miR-17, -18a, -19a, -20a, -19b-1, and -92a-1) regulates angiogenesis in multiple settings, but no definitive role in renal endothelium during...

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Bibliographic Details
Published in:J Am Soc Nephrol
Main Authors: Chiba, Takuto, Cerqueira, Débora M., Li, Yao, Bodnar, Andrew J., Mukherjee, Elina, Pfister, Katherine, Phua, Yu Leng, Shaikh, Kai, Sanders, Brandon T., Hemker, Shelby L., Pagano, Patrick J., Wu, Yijen L., Ho, Jacqueline, Sims-Lucas, Sunder
Format: Artigo
Language:Inglês
Published: American Society of Nephrology 2021
Subjects:
Rapid Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7920169/
https://ncbi.nlm.nih.gov/pubmed/33514560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2020050717
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