Bim gene dosage is critical in modulating nephron progenitor survival in the absence of microRNAs during kidney development

Low nephron endowment at birth has been associated with an increased risk for developing hypertension and chronic kidney disease. We demonstrated in an earlier study that conditional deletion of the microRNA (miRNA)-processing enzyme Dicer from nephron progenitors results in premature depletion of t...

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Detalles Bibliográficos
Publicado en:FASEB J
Main Authors: Cerqueira, Débora M., Bodnar, Andrew J., Phua, Yu Leng, Freer, Rachel, Hemker, Shelby L., Walensky, Loren D., Hukriede, Neil A., Ho, Jacqueline
Formato: Artigo
Idioma:Inglês
Publicado: Federation of American Societies for Experimental Biology 2017
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503708/
https://ncbi.nlm.nih.gov/pubmed/28446592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700010R
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